E-ISSN 2683-0906
 

Original Article 


The effect of cashew (Anacardium occidentale l.) nut oil on the blood, liver and kidneys of male Wistar rats

Joseph Onoriode Akpotu, Sonnie Joshua Oniye, Shuaibu A. Abdullahi, Bitrus T. Magaji.

Abstract
The possible toxicity effect of Anacardium Occidentale nut oil on the blood, liver and kidneys of male Wistar rats was investigated. Phytochemical screening was conducted on the oil to determine its antinutrient composition. The rats were assigned to three treatment groups i.e 0.027mLg-1, 0.081mLg-1, 0.162mLg-1 and a control group. The oil was administered to the rats through the oral route daily for 28 days. Blood samples were collected on a weekly basis for haematological screening throughout the period of the experiment. The haematological result showed a slight deviation from the normal in packed cell volume (52%), total white blood cell count (9.38) and lymphocyte count (58.17) in Wistar rats administered 0.081 to 0.162mLg-1 of the cashew nut oil respectively yet no visible compromise of the immune system was observed. Histological analysis, however, revealed some hepatocyte morphological lesions including microvesicular steatosis and necrosis, kupffer cell hyperplasia, shrinkage of glomeruli, glomerular distortion, necrotic renal tubules, severe congestion and atrophy of renal tubules in rats fed 0.162mLg-1 of the nut oil. In conclusion, the cashew nut oil was responsible for hepatic parenchymal and matrix alteration in Wistar rats following sub-chronic treatment at 0.162mLg-1.

Key words: cashew nut oil, toxicity, sub-chronic treatment, immune response and hepatic lesion


 
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How to Cite this Article
Pubmed Style

Akpotu JO, Oniye SJ, Abdullahi SA, Magaji BT. The effect of cashew (Anacardium occidentale l.) nut oil on the blood, liver and kidneys of male Wistar rats. Int J Agric Biotechnol Food Sci. 2021; 2(1): 13-19. doi:10.5455/ijabfs.THEEFFECTOFCASHEWANACARDIUMOCCIDENTALEL.NUTOILONTHEBLOODLIVERANDKIDNEYSOFMALEWISTARR


Web Style

Akpotu JO, Oniye SJ, Abdullahi SA, Magaji BT. The effect of cashew (Anacardium occidentale l.) nut oil on the blood, liver and kidneys of male Wistar rats. https://www.agropub.net/?mno=102212 [Access: June 05, 2022]. doi:10.5455/ijabfs.THEEFFECTOFCASHEWANACARDIUMOCCIDENTALEL.NUTOILONTHEBLOODLIVERANDKIDNEYSOFMALEWISTARR


AMA (American Medical Association) Style

Akpotu JO, Oniye SJ, Abdullahi SA, Magaji BT. The effect of cashew (Anacardium occidentale l.) nut oil on the blood, liver and kidneys of male Wistar rats. Int J Agric Biotechnol Food Sci. 2021; 2(1): 13-19. doi:10.5455/ijabfs.THEEFFECTOFCASHEWANACARDIUMOCCIDENTALEL.NUTOILONTHEBLOODLIVERANDKIDNEYSOFMALEWISTARR



Vancouver/ICMJE Style

Akpotu JO, Oniye SJ, Abdullahi SA, Magaji BT. The effect of cashew (Anacardium occidentale l.) nut oil on the blood, liver and kidneys of male Wistar rats. Int J Agric Biotechnol Food Sci. (2021), [cited June 05, 2022]; 2(1): 13-19. doi:10.5455/ijabfs.THEEFFECTOFCASHEWANACARDIUMOCCIDENTALEL.NUTOILONTHEBLOODLIVERANDKIDNEYSOFMALEWISTARR



Harvard Style

Akpotu, J. O., Oniye, . S. J., Abdullahi, . S. A. & Magaji, . B. T. (2021) The effect of cashew (Anacardium occidentale l.) nut oil on the blood, liver and kidneys of male Wistar rats. Int J Agric Biotechnol Food Sci, 2 (1), 13-19. doi:10.5455/ijabfs.THEEFFECTOFCASHEWANACARDIUMOCCIDENTALEL.NUTOILONTHEBLOODLIVERANDKIDNEYSOFMALEWISTARR



Turabian Style

Akpotu, Joseph Onoriode, Sonnie Joshua Oniye, Shuaibu A. Abdullahi, and Bitrus T. Magaji. 2021. The effect of cashew (Anacardium occidentale l.) nut oil on the blood, liver and kidneys of male Wistar rats. International Journal of Agricultural Biotechnology and Food Sciences, 2 (1), 13-19. doi:10.5455/ijabfs.THEEFFECTOFCASHEWANACARDIUMOCCIDENTALEL.NUTOILONTHEBLOODLIVERANDKIDNEYSOFMALEWISTARR



Chicago Style

Akpotu, Joseph Onoriode, Sonnie Joshua Oniye, Shuaibu A. Abdullahi, and Bitrus T. Magaji. "The effect of cashew (Anacardium occidentale l.) nut oil on the blood, liver and kidneys of male Wistar rats." International Journal of Agricultural Biotechnology and Food Sciences 2 (2021), 13-19. doi:10.5455/ijabfs.THEEFFECTOFCASHEWANACARDIUMOCCIDENTALEL.NUTOILONTHEBLOODLIVERANDKIDNEYSOFMALEWISTARR



MLA (The Modern Language Association) Style

Akpotu, Joseph Onoriode, Sonnie Joshua Oniye, Shuaibu A. Abdullahi, and Bitrus T. Magaji. "The effect of cashew (Anacardium occidentale l.) nut oil on the blood, liver and kidneys of male Wistar rats." International Journal of Agricultural Biotechnology and Food Sciences 2.1 (2021), 13-19. Print. doi:10.5455/ijabfs.THEEFFECTOFCASHEWANACARDIUMOCCIDENTALEL.NUTOILONTHEBLOODLIVERANDKIDNEYSOFMALEWISTARR



APA (American Psychological Association) Style

Akpotu, J. O., Oniye, . S. J., Abdullahi, . S. A. & Magaji, . B. T. (2021) The effect of cashew (Anacardium occidentale l.) nut oil on the blood, liver and kidneys of male Wistar rats. International Journal of Agricultural Biotechnology and Food Sciences, 2 (1), 13-19. doi:10.5455/ijabfs.THEEFFECTOFCASHEWANACARDIUMOCCIDENTALEL.NUTOILONTHEBLOODLIVERANDKIDNEYSOFMALEWISTARR